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What is open science?

Extract from Living in an Ivory Basement by Titus Brown –October 24, 2016 Some background: Science advances because we share ideas and methods Scientific progress relies on the sharing of both scientific ideas and scientific methodology – “If I have seen further it is by standing on the shoulders of Giants” (https://en.wikipedia.org/wiki/Standing_on_the_shoulders_of_giants). The natural sciences […]

Issue Septembre 2016

Can you teach old drugs new tricks? Faced with skyrocketing costs for developing new drugs, researchers are looking at ways to repurpose older ones — and even some that failed in initial trials. read more How overcome the challenges of DRPx strategies? Drug Repurposing (DRPx), also commonly referred to as Drug Repositioning or Drug Rescue, […]

How overcome the challenge of drug repositioning?

Drug Repurposing (DRPx), also commonly referred to as Drug Repositioning or Drug Rescue, emerged primarily in the early 1990s as an alternative to conventional de novo DDD. DRPx is defined more specifically as the process of finding new indications for approved drugs, abandoned or shelved compounds and candidates under development. DRPx is a complex process […]

Issue July 2016

How to Survive the Valley of Death as a Biotech Startup? Contributing post from Peter Machin, former SVP Drug Discovery at GSK- La Biotech Juin 2016 Over the past decade there has been an unprecedented restructuring of R&D in pharma whereas building a successful biotech company is still as challenging. How can these two elements […]

Spreadsheets vs databases: The right tool for the right job

Having consistent, reliable, and cross-linked data is one of the biggest challenges facing pharmaceutical RD. Although some data needs to be structured and aggregated, other data or documents need only to be indexed or stored. When do you use a spreadsheet, or when do you need a database? Both application types are useful but they […]

Biocorpora: a collaborative tool to leverage internal cooperation

When we talk about collaboration or knowledge sharing, we often refer to external collaboration. The fact is that there are two types of collaboration: internal and external. The goal with both types of collaboration is very similar: get people to work together in a way that provides tangible benefits to common projects, while facilitating achievement […]

Biocorpora: Progress a hit into a lead

The idea for a target can come from a variety of sources including academic researches, or researches from the commercial sector. The initial research generates data to develop a hypothesis that the activation of a protein will result in a therapeutic effect in a disease state. The outcome of this activity is the selection of […]

Biocorpora: Choose the way you share your data

Sometimes, sensitive and confidential data must be safeguarded by restricting access while, at the same time, one needs to enable data sharing for collaborative research or external cooperation. How to find the best way between open sharing models and exclusively closed access? Open and private sharing models can coexist to promote collaboration while safeguarding intellectual […]

Release 3.15 – 15 Dec 2015

Scaligner Added Kabat numbering Added germline editor Added germline sets to run analysis on a subset of all germlines available Biocorpora Added report caching for faster report display Improved user interface for report edition Improved Javascript molecule editor