Scaligner Added interface to load, process and visualize NGS datasets.
Biocorpora Improved change tracking in registration module. All the editable fields about a registered entity are traced. Change display has been improved. Unmodified fields are not listed in the change report. Added more explicit error messages when a required value is missing from a form.
Biocorpora Added support for multiple data sources in reports. Until version 3.24, reports were based on a single data source, it was therefore necessary to have all the data in the same database view. A report can now contain nested reports based on multiple data sources. The main benefit is to reduce the number of […]
Scaligner Added humanness scores to the Excel export file. Fixed display issue with humanness graphs in Chrome. Limit the number of CDR3 shown in a clonotypes. Bug fix in AHo numbering. Enable gap suppression in consensus sequence in the clustering module.
Scaligner Update for clustering module Clusters start with #1 instead of #0. Added the functionality to select all the sequences of a cluster, and send them to the alignment window Improved the Excel clustering report (title, headers, full length consensus sequence) Added tooltips for sequence selection and sorting.
Scaligner After many new functionalities have been added over the last years, Scaligner’s source code is reviewed in depth to provide a consistent and more user friendly display of the information. A new option has been added prevent fixing automatically frameshifts during the processing of sequences. When fixes are allowed (behavior until 3.23), some nucleotides […]
When a sequence is quite dissimilar from any germline, the alignment algorithm tends to add gaps here and there to increase similarity with the choosen germline. From 3.24, a post-alignment procedure enables aminoacid rearrangement to make the CDR look like an IMGT CDR, even when the alignment has created gaps in the CDR. This procedure […]
The redundant network connection has been interrupted at the primary datacenter around 10 minutes around 15:15 today. All the services are now up.
Scaligner New module to analyze and visualize NGS data based on clonotype analysis The NGS module can analyze millions of antibody sequences from several animals Sequences are processed by Scaligner using a procedure similar to the one described by Trinklein et al (in section “Variable region amplification, sequencing, and clonotype analysis”). Clonotypes are stored and […]
LTS for OpenSSL 1.0.2 ended on the 31st of December 2019 Added support for TLS 1.3