Scaligner After many new functionalities have been added over the last years, Scaligner’s source code is reviewed in depth to provide a consistent and more user friendly display of the information. A new option has been added prevent fixing automatically frameshifts during the processing of sequences. When fixes are allowed (behavior until 3.23), some nucleotides […]

Scaligner (NGS) New module to analyze and visualize NGS data based on clonotype analysis The NGS module can analyze millions of antibody sequences from several animals Sequences are processed by Scaligner using a procedure similar to the one described by Trinklein et al (in section “Variable region amplification, sequencing, and clonotype analysis”). Clonotypes are stored […]

Scaligner Added AHo numbering Change default numbering for all users Import sequence by sequence manually Display similarity and percent identity in Excel export Change default sort scoring from Blosum30 to %Identity Search region across database Search window is no more limited to 20 sequences Calculate CDR3 frequency across database Choose the order to display VH […]

Scaligner handle complementary sequences improved sequence detection (handles wildcard for amino acids an nucleotide sequences) display PTM location in sequence log speed up sequence analysis Documents added support for WebDAV protocol speedup document upload in DocExplorer

Scaligner improved user interface for editing aggregated reports automated cache cleanup Compound browser optimized speed for name lookups Document added support for recursive document checkout added ability to document new documents

DocExplorer added support for large files (10+Gb) better integration with Windows Explorer (Drag and Drop) Base plateform improved session management, and improved the response to end-of-sessions

Inventory several new functionalities for ID generation, display, search Scaligner amino acid sequence alignment DocExplorer added a new Java WebStart plugin named DocExplorer to access the document stored in the database

Biocorpora New compound ordering module New experiment request module, based on the inventory Many graphical improvements

Biocorpora Easier management of study reports from the interface Improved report caching Started migration to new modular architecture

Scaligner Added Kabat numbering Added germline editor Added germline sets to run analysis on a subset of all germlines available Biocorpora Added report caching for faster report display Improved user interface for report edition Improved Javascript molecule editor